Deals & Financing

Licensing, acquisitions, financings and clinical readouts that matter for China-originated assets and the buyers looking at them, each linked to the company announcement or trade-press source. Upfront and milestone amounts are listed separately, as disclosed.

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Companies

Estuary Bio raises $103M to advance local AAV therapy for ADPKD

$103M total
Financing

AstraZeneca and insitro form a strategic collaboration in difficult-to-treat cardiometabolic disease

$40M upfront
Licensing

OMass Therapeutics raises a $310M Series C

$310M (GBP230M)
Financing

City Therapeutics prices upsized IPO at about $200M

About $200M
Financing

CSPC announces China IND for SYS6088, a PD-1/VEGFA/CTLA-4 trispecific

No deal value
Clinical

Eton licenses US rights to Aquestive's Libervant (diazepam buccal film)

$10M upfront
Licensing

Hiteck licenses next-generation NGF eye drop HT006.2.2 to Visara outside Greater China

$7M upfront and near-term
Licensing

MicuRx licenses MRX-23 ADC and grants STOPIN platform options to ClearideBio

$1M upfront
Licensing

Asieris grants Theramex exclusive rights to APL-1702 (CEVIRA) in Europe and other markets

Over $250M total
Licensing

Garden Bio and Guangzhou National Laboratory form a joint venture for 25-hydroxycholesterol broad-spectrum antivirals

Undisclosed
NewCoLicensing

Sino Biopharm completes enrollment in Phase 3 registrational trial of inhaled TQC3721 for COPD

No deal value
Clinical

CSPC updates Phase 1 data for SYS6002 in advanced cervical cancer; 2.4 mg/kg regimen moves into Phase 3

No deal value
Clinical

Novartis takes global rights to Abogen's in vivo mRNA T-cell engager ABO2203

$575M upfront; up to ~$7.8B total
Licensing

GSK buys Chimagen's trispecific T-cell engager for up to $750M

Up to $750M total
M&A

Ivonescimab monotherapy beats pembrolizumab on overall survival in HARMONi-2

No deal value
Clinical

Simcere Zaiming licenses CD79a×CD19×CD3 trispecific SIM0660 to Roche

Up to $1.53B total
Licensing

Lilly to acquire Merida Biosciences for up to $2.9B, entering Graves' disease

Up to ~$2.88B total
M&A

Haisco immunology asset goes into ARCH-founded NewCo Sentivera

Over $1.5B total
NewCoLicensing

J&J locks up Sail Biomedicines' in vivo CAR-T with an equity stake and an acquisition option

$2.58B total if the acquisition option is exercised
LicensingFinancing

argenx to acquire Forte for $2.2B, adding anti-CD122 antibody FB102

~$2.2B in cash
M&AClinical

GemPharmatech and Humlab partner on global distribution of humanized mouse models

Undisclosed
Licensing

Avere in-licenses Hansoh's oral IL-23 drug, lists via NextCure reverse merger and raises $320M

License up to $2.3B; concurrent $320M private placement
NewCoLicensingFinancing

AstraZeneca and CSPC partner on kidney-disease siRNA

~$1.77B total
Licensing

Insilico Medicine and Takeda sign AI drug discovery collaboration

~$600M total
Licensing

Lilly to acquire in vivo CAR-T company Kelonia for up to $7B

Up to $7B in cash
M&AClinical

Annual tally

China innovative-drug out-licensing
YearDealsTotal valueUpfront payments, combined
202494$51.9B—
2025157$135.7B$7.0B

Data from DIA Global Forum, March 2026. Upfront payments were only about 5% of total value; the rest is paid only if development reaches agreed milestones, and much of it never will be.